Valdoxan: A Remedy To Beat The Blues Of Depression

08.02.18 Posted By Charles Bowers

Feeling, sad or low, loss of interest or pleasure in day to day activities are feelings familiar to us all yet to some of us these are the most common persistent and dominant feelings.  After a point, it becomes a mental health issue and is known as Depression. A few common symptoms of this condition are reduced joy and interest in things that generally amuse people. Depression is a complex situation with possible links to and even a combination of genetic, biological, environmental, and psychosocial factors. This is a mood disorder and should not be mistaken with behavioral changes due to bereavement. Depression is not a passing problem is a lasting one and can stay for 6 to 8 months on an average.

This condition is mostly symptomatically diagnosed by a doctor. It gets important for a person suffering from depression to visit a doctor or therapist at the right time as this helps in charting out the specific cause of depression, make an accurate diagnosis and figure out specific treatment options. For an effective diagnosis, you may go through a physical examination to find out any linkage or any coexisting factor, the doctor will go through the family history, there are set of questionnaires a person has to answer, this helps the doctor in finding the severity of the condition and rate it, one such scale widely used is Hamilton scale which has a set of 21 questions used as an assessment tool for rating depression.


Valdoxan 25 mg is one of the most popular drugs used worldwide for the competent management of Depression and major depressive disorder. This drug is used as the Valdoxan is used by leading physicians across the globe as the first line management of Depression and major depressive disorder. Valdoxan imparts its positive effects by mitigating the gloomy and sad thoughts by uplifting the mood of the user, this drug also acts by mediating the sleep-wake cycle by regulating the melatonin onset, this hormone is essential for the maintenance of circadian cycle in the body. This makes a person feel calm and happy and forgets depression or major depressive disorder.

Agomelatine is the key therapeutic agent in Valdoxan. It belongs to the class of anti-depressant medications which acts a melatonin agonist and antagonist of serotonin receptors which are located in the brain. Agomelatine has therapeutic effects on a depressed mind as it induces a phase of sleep, declines the body temperature and regulates the melatonin onset. Its action on Serotonin receptors also has an important role to play in the management of depression.

Valdoxan can be accessed in dosing strength of 25mg; it is an oral preparation which should be taken with ample amount of water. You can take Valdoxan irrespective of food. The most used dosing regimen for the management of Depression is one Valdoxan 25mg taken each day orally, preferably at bedtime with water for the required duration of time. The present dose can be increased to 50mg taken each day which would be two tablets as a single dose at bedtime. 

Associated side effects of Valdoxan:

A few side effects of this medication are listed below 

  • Dizziness, nausea, diarrhea,
  • Abdominal cramp, vomiting
  • Back pain, fatigue
  • Constipation, migraine

Preventive measures of this therapy: 

  • The use of alcohol is not feasible for this condition and interferes with this therapy, it can postpone the onset of medication and worsen the side effects.
  • Valdoxan has sedative effects, it makes a person feel drowsy and lightheaded even in the day hours, you are advised not to drive or do any such activity till you know how you respond to this medication.
  • Tell your doctor about all the drugs you are using with Valdoxan.

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